Severe cutaneous eruptions on telaprevir
نویسندگان
چکیده
منابع مشابه
Cutaneous drug eruptions.
Patients attending a referral Skin Clinic were studied to identify the spectrum of drug eruptions and the offending drugs. There were 51 patients with an incidence of five per thousand and equal sex incidence. Though the pattern of eruption was broadly similar to other reports, unusual reactions were observed. In addition to the skin manifestation, fever and lymphadenopathy were present in most...
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Hepatitis C virus (HCV) chronically infects 0.5-3% of the world population. A large group of patients develop cirrhosis and its complications. Since 2011, telaprevir and boceprevir are used, improving the disease evolution. One of the main side effects of these drugs is skin eruption. We report a 53-year-old patient with cirrhosis due to HCV who started the classic treatment associated with tel...
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Macular and papular eruptions are ascribed to various causes, often drug-related hypersensitivity or toxicity. We observed patients with cutaneous eruptions during hospital admissions for induction or augmentation chemotherapy in the treatment of leukemia. In 10 of 14 patients, macular and papular eruptions occurred in a strikingly similar pattern, at the earliest recovery of peripheral lymphoc...
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A 53-year-old woman developed an intensely pruritic rash on the plantar aspect of her right foot within 1 week of returning from a vacation in Jamaica, where she had walked barefoot on the beach (Fig. 1). The pattern revealed a classic serpiginous, elevated, erythematous lesion consistent with cutaneous larva migrans (CLM). CLM is the most common travel-associated dermatological infection prese...
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It remains unknown how autoimmunity is elicited, although many different mechanisms have been involved. There is a major difficulty in establishing a correlation between triggering events and the actual autoimmune disease because of long prodromal period. In this regard, previous studies reported that sera obtained from the acute stage of SJS/TEN and erythema multiforme contain autoantibodies (...
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ژورنال
عنوان ژورنال: Journal of Hepatology
سال: 2012
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2012.02.004